bulk rna sequencing Search Results


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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Bulk Or Single Cell Rna Sequencing, supplied by Federation of European Neuroscience Societies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Bulk Rna Sequencing, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Lexogen GmbH bulk rna sequencing
Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Verum Diagnostica GmbH bulk rna sequencing dataset
Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk <t>RNA-seq.</t> (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Image Search Results


Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk RNA-seq. (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Journal: Materials Today Bio

Article Title: Replenishment of mitochondrial Na + and H + by ionophores potentiates cutaneous wound healing in diabetes

doi: 10.1016/j.mtbio.2024.101056

Figure Lengend Snippet: Monensin An up-regulates mitochondrially encoded genes. (A) Overview of the monensin A mediated alteration of gene expression on HACAT cells using bulk RNA-seq. (B) Pathway enrichment analysis arranging the top up-regulated pathways according to the adjusted p-value (left). The altered information on the top-ranking pathway was further excavated (right). (C) Heatmap shows monensin A-triggered actively expressed genes involved in the top-ranking pathway. Data are color-coded to reflect the relative expression level of mitochondrially encoded genes. All data are normalized to their matched control. (D) PCR-based validation of the mRNA expression of mitochondrial genes in HACAT cells treated with or without monensin A (125 nM) for 3 h. Data are represented as mean ± SD. Two-tailed Student's unpaired t -test (D). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Article Snippet: RNA samples were submitted to LC Sciences (Hangzhou, China) for bulk RNA sequencing using the Illumina platform.

Techniques: Gene Expression, RNA Sequencing, Expressing, Control, Biomarker Discovery, Two Tailed Test